Biological Sciences

Cohesin complex structure and chromatin loop formation for transcription regulation.

This scientific illustration details the cohesin complex and its role in chromatin loop formation and gene regulation. The complex is composed of Smc2, Smc4, and kleisin, with coiled-coil domains connected by hinge and head regions. These structural elements enable the cohesin complex to bind chromatin fibers, facilitating chromatin looping. The loops, shown in this diagram, play a vital role in gene transcription regulation by bringing enhancers and promoters closer together.

This illustration is ideal for use in molecular biology textbooks, genomics journals, and educational articles focused on chromatin architecture, cohesin function, and transcription regulation.

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